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There were 13 preclinical trials conducted on animal models of PD, of which ( n = 5) were conducted on the Drosophila melanogaster fruit fly model [2426, 28, 29], ( n = 4) on the Sprague-Dawley rat model [3336], ( n = 3) on the Swiss albino rat model [27, 30, 31], and one ( n = 1) was conducted on the monkey [32]

Acknowledgements This work was supported by the BK21 FOUR (Fostering Outstanding Universities for Research) and the Basic Science Research Program through the National Research Foundation of Korea (NRF), by the Ministry of Science and ICT (MSIT) (2022R1A2C1004204), and by the Soonchunhyang University Research Fund

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The time it takes for Glutathione to work varies from person to person

Lower RMSF values indicate more stiff and stable areas, whereas higher RMSF values imply more residue flexibility, which increases the chance of interacting with ligand molecules 86