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Description
This means that a peptide with a 2-hour half-life administered three times daily will reach steady-state within approximately 10 hours, while a peptide with a 7-day half-life like Semaglutide requires roughly 35 days to reach steady state with weekly dosing

[Medline: 26297393] [doi: 10.1016/j.oooo.2015.05.008] Amrigo-Gngora M, Machuca-Portillo G, Torres-Lagares D, Lesclous P, Amrigo-Navarro J, Gonzlez-Cmpora R

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[Google Scholar] 5.Laumann EO, Paik A, Rosen RC
