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Description
Tricyclic antidepressants including imipramine and amitriptyline are a mainstay of treatment for a variety of chronic pain states, although not FDA-approved for this indication (Tauben & Stacey, 2021)
International Journal of Clinical Pharmacology, Therapy, and Toxicology 1986;24(9):5116
doi: 10.1186/s13024-019-0332-6
Rabinovitch, M., Guignabert, C., Humbert, M
The safest interpretation is that without explicit Category 1 placement, compounding carries significant regulatory uncertainty
