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Later studies, combining purified human proteins or human liver microsomes with specific inhibitors confirm the role of CYP2E1 in bioactivation of toxic levels of APAP, but also report involvement of CYP2A6 [31,32]

HBS-EP+ buffer with 1% DMSO was used as running buffer and for the preparation of all analyte samples

Neither the molecular weight (data not shown) nor an increase in TW CCS N2 could be identified as a root cause

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