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PMID: 16996037), a single intranasal application of Semax at 50 g/kg in rats produced a maximal 1.4-fold increase in hippocampal BDNF protein levels, a 1.6-fold increase in TrkB tyrosine phosphorylation, a 3-fold increase in exon III BDNF mRNA, and a 2-fold increase in TrkB mRNA effects observed within hours of a single administration

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Delir) sind trizyklische Antidepressiva im Alter zu vermeiden und Serotonin-Wiederaufnahmehemmer (SSRI), Mirtazapin oder Agomelatin zu bevorzugen

Autophagy is primarily governed by LC3 proteins, specifically microtubule-associated protein 1 light chain 3 (MAP1LC3), commonly known as LC3