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It is on this basis of such duality that the therapeutic context, whether one wishes to inhibit or induce pathological angiogenesis in tumors or reparative angiogenesis in degenerative diseases must be defined before a therapeutic can be applied in a clinical patient
doi: 10.1111/jhn.12372
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In the transgenic AD mouse model Tg2576, marked by mutant APP overexpression in the brain, melatonin treatment exhibited a trend of elevated A levels in cervical and axillary lymph nodes, concomitant with a decreasing trend in brain A [76]
Metabolic basis of inherited disease
