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Membrane-anchored serine proteases in health and disease

Since tirzepatide may slow gastric emptying as part of its mechanism of action, patients with pre-existing severe gastroparesis could experience worsening of symptoms, including nausea, vomiting, and potential complications related to delayed gastric emptying

The MAPK cascade represents a primary signaling axis downstream of LOX-1 activation

A non-linear dose-response relationship was observed between L-Carnitine supplementation and weight loss, suggesting that 2000 mg of L-Carnitine daily provides the maximum effect in adults

Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model