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What the FDA approval process exists to determine isn't whether something might work

10.1038/s41598-021-81997-9 14 BarrosT

95% CI 1.60 to 1.66
NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's disease
irregularities in their function may lead to apoptosis, alterations to signaling pathway function, and, ultimately, compromised fertility
