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Long-term reactions are still unclear

Promotion of lipolysis (fat breakdown) in experimental models

The cardiovascular and respiratory side effects include chest pain, tachycardia (increased heart rate), heart palpitations, low blood pressure, and chest tightness, cough with or without production of pink frothy sputum, wheezing and difficulty breathing

Daily doses of 125 mg/kg for up to 11 days induced vomition, inappetence, depression, difficult locomotion and death while adult dogs receiving 50 mg/kg/day for 14 days had clinical signs of vomition and inappetence

In this study, certain discrepancies in clinicopathological and surgical characteristics were noted between the PG-DTR and TG groups
