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For more complex systems these results indicate that too long treatment times can cause difficult-to-handle modifications to the cellular redox buffer which can impair proper cellular function.

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a 16-amino acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA

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Its importance lies in the fundamental role it plays in the transport of fatty acids into the mitochondria