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The Pro63, Asp75, and Tyr97 residues are required for GSH oxidation by Og cytAPX1, whereas the corresponding site in At APX1 is composed of Asp63, His75, and His97, and has no GSH binding activity

Alabi1,2, Abayomi M, Ajayi2, Benneth Ben-Azu2,3, Osarume Omorobge2, Solomon Umukoro (2019) Methyl jasmonate ameliorates rotenone-induced motor deficits in rats through its neuroprotective activity and increased expression of tyrosine hydroxylase immunopositive cells, Metabolic Brain Disease Received: 16 March 2019 /Accepted: 5 August 2019 Alabi AO, Ajayi AM, Ben-Azu B, Bakre AG, Umukoro S (2019a) Methyl jasmonate abrogates rotenone-induced parkinsonian-like symptoms through inhibition of oxidative stress, release of pro-inflammatory cytokines, and down-regulation of immnopositive cells of NF-B and -synuclein expressions in mice

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Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations