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132 Another controlled trial that included 120 subjects with tinnitus and low cochlear blood flow related to Mnire disease found 150 mg of Pycnogenol per day for six months improved cochlear blood flow and reduced subjective measures of tinnitus compared with no treatment

The primary mechanism of AOD-9604 in laboratory research models is selective beta-3 adrenergic receptor (beta-3 AR) activation
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