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What remains unknown Despite encouraging data, genuine unknowns exist: Effects beyond 6-9 months of continuous use have not been formally studied in animals or humans

Based on the data available in 2015, EFSA did not identify any known health risks associated with the use of dietary supplements, so no maximum dose or maximum daily intake, also known as a tolerable upper intake, was set (EFSA, 2015)

2) Treatment with AOD9604 has been found to increase expression of beta-3-AR RNA, indicating that the compound has the potential to enhance lipolytic sensitivity

This notion gains further support from recent experimental endeavors

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