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however, in overexpression, it can lead to neuroinflammation

Monitoring: Clinicians typically track melatonin rhythm, cortisol patterns, inflammatory markers (hs-CRP), and in some cases, telomere length via commercial testing as a baseline and follow-up tool

demonstrated that the balance of the CoQH 2 :CoQ ratio serves as a sensor for respiratory chain efficiency and that an increase in this ratio underlies ROS generation via RET 26

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These interactions complicate risk assessment and mitigation efforts, as the overall toxicity may be greater than the sum of individual effects [39]
