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The peptides ability to cross the blood-brain barrier opens possibilities for central nervous system applications

The peptides lack of interaction with the GH receptor is particularly relevant for joint applications

Microbiol Spectr 5(5):BAD-0018-2016

Nader MA, Ateyya H, El-Shafey M, El-Sherbeeny NA (2018) Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: implication of oxidative, inflammatory, apoptotic and autophagy pathways

These results deepen our understanding of the crosstalk between cancer cells and nerves in pancreatic cancer