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During hyperglycaemia, elevated O-GlcNAc modification of the transcription factor specificity protein 1 (SP1) increases ICAM-1 expression in HUVECs and rat retinal capillary endothelial cells and upregulates VEGF-A expression in retinal cells [55, 56]

Innovation in Processing New processing techniques are being developed to preserve even more of cacao's beneficial compounds while improving flavor and texture

In turn, three moles of five-carbon sugar are converted, via the enzymes of the PPP, back into two moles of six-carbon sugars and one mole of three-carbon sugar