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Oral glutathione largely fails because it breaks down in the gut before reaching circulation

Ramifications of Thiamine Deficiency Department of Natural Resources, Cornell University, 2017

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It helps mood and sleep patterns by helping the body produce serotonin, melatonin, and norepinephrine, a stress hormone

The metabolites END and 4-OH-TAM have a 100 times stronger affinity to estrogen receptors in comparison to TAM 6,27,28