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Physiologically active form of AsA is the resonance stabilized anionic form (formed due to deprotonation of the hydroxy group at C 3 ) which is termed as ascorbate

doi: 10.3390/biom13091291

Regenerative medicine-based solutions are being aggressively pursued with the goal of restoring dopamine levels in the striatum, with several emerging techniques attempting to reconstruct the entire nigrostriatal pathwaya key goal to recreate feedback pathways to ensure proper dopamine regulation

For instance, compensatory brain changes due to D2 antagonists can lead to increased sensitivity to dopamine receptor stimulation, known as dopamine receptor supersensitivity [232]
