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The roles of LDL-C, HDL-C, and CETP in the retina, along with their influence on the eye lens, intraocular pressure, and local cholesterol metabolism, are not yet fully understood

2017;96:e7637

To clarify this, we subjected wt worms to gsy-1 and daf-16 double RNAi treatment

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We used Crispr-Cas9 gene editing to reproduce the zu501 mutation in otherwise wild-type animals, and found that the resulting nemp-1(zu522) animals appeared identical to nemp-1(zu501)