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Its primary mechanism involves upregulation of the hTERT gene, which encodes the catalytic subunit of telomerase -- the enzyme that adds TTAGGG repeats to chromosome ends
In the case of LSEC zonation, we did not detect significant differential expression of LSEC markers or gene signatures in the EC clusters, indicating that zonation is not yet established in our model
Users are essentially participating in uncontrolled self-experimentation, a reality that informed decision-making requires acknowledging

Oxidative stress primarily damages the unsaturated fatty acids in cell membranes, leading to cellular dysfunction

Oncologist 17, 11081113
