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Effectivecombinationtherapiesareurgentlyneededtotreattriple-negativebreastcancer(TNBC),whichisinsensitivetotheexistingtreatmentregimens.However,thesynergisticpotencyoftraditionalsmall-moleculecombinationsislimitedmainlyduetomismatchedmolarratios,inconsistentpharmacokinetics,andintratumoralaccumulationofindividualdrugs.Currentnanotechnologyoffersanunparalleleddevelopmentonadvancedcombinationdrugdelivery,especiallyratiometricdrugdeliveryinvivo.Recently,Prof.LIUXiangruiandProf.ZHOUTianhuafromtheZhe
Researchers who hit a visible stall, added a support compound, and are still not seeing improvement because the original bottleneck was never correctly identified