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Mitochondrial abnormalities have also been associated with point mutations in Hsp70 chaperone that makes it aggregation prone, thereby, increasing iron and free-radical load 15,16,17

Dulken, B

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doi: 10.1016/j.semarthrit.2016.08.012 17 ZachrissonO.ReglandB.JahreskogM.KronM.GottfriesC

Neuropeptides 46 , 183193 (2012)