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Aged mice were intraperitoneally injected with 5 mg/kg FOXO4-DRI or PBS as a control every other day for three administrations, and effects were assessed 30 days post-treatment

The most substantial evidence comes from a 2010 randomized controlled trial involving 40 healthy adults who received intravenous doses ranging from 42 to 1,260 mg of thymosin beta 4

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