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Instead of a balanced progression, hair follicles prematurely shift into the telogen phase, resulting in excessive shedding, also known as telogen effluvium

GH exerts autocrine/paracrine effects by binding to GHR in the same or a neighboring cell surface and initiating JAK2- and SRC-mediated signaling cascades, which decrease pro-apoptotic molecules (Bax and PPAR) and suppress caspase protein activation (Figure 4A)

Lancet Rheumatol (2020) 2(12):e741

78,86,180 Neurotrauma boosts neurogenesis and migration of neuroblasts into the perilesional penumbra, where they arguably contribute to the neuronal circuitry repair

& Nestle, F