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injectable use remains investigational

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Pemetrexed administered intraperitoneally at doses of 0.1 mg/kg/day to male mice (approximately 0.0006 times the recommended human dose based on BSA) resulted in reduced fertility, hypospermia, and testicular atrophy

In addition, UDCA avoids efficiently the enhancement in LC3II protein expression and in the number of AVOs in enterocytes caused by NaDOC, which means that UDCA attenuates the biomarkers of autophagy[22]

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