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Upon activation, microglia produce pro-inflammatory cytokines which can increase permeability of the BBB, allowing passage of immune cells into the brain parenchyma [15]

J Biomol Struct Dyn 39(9):33473357 de Siqueira Patriota LL, de Ramos DBM, Dos Santos ACLA, Silva YA, Silva EMG, Torres DJL et al (2020) Antitumor activity of Moringa oleifera (drumstick tree) flower trypsin inhibitor (MoFTI) in sarcoma 180-bearing mice

Peroxisomes produce ROS and reactive nitrogen species (RNS), such as H 2 O 2 , O 2 , OH, NO, and ONOO [17]

Therefore, the presence of CYP2J19 genes plays a crucial role in the ketolation of carotenoids in avian and reptilian species