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[DOI] [PMC free article] [PubMed] [Google Scholar] 435.Hourihan, J

In innate immunity, Clostridium modulates macrophage polarization (shifting from pro-inflammatory M1 to anti-inflammatory M2), induces tolerogenic dendritic cell phenotypes to suppress excessive antigen presentation, regulates inflammatory body activity and neutrophil hyperactivation, and modulates ILC subsets to reinforce mucosal defense

doi: 10.1016/0735-1097(95)80010-E

NLRP3 specifically interacts with NEK7, and after the activation of the inflammasome, the NEK7-NLRP3 interaction increases, leading to the oligomerization of NEK7 with NLRP3 into a complex

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