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Animals were euthanized 1 h after caffeine injection, and brain tissues were biochemically examined for oxidants and antioxidants

Studies in GHD patients receiving hGH therapy report [15]: Improved quality of life 2-5% increase in lean muscle mass 7-10% lower fat mass and a -1.2inch mean decrease in waist circumference 11-16% lower LDL (bad) cholesterol Yet, the benefits of hGH therapy in otherwise healthy individuals appear to be more modest

Fibroblast Growth Factor 21 Exerts Direct Anti-Fibrotic Effects FGF21 and its analogs have demonstrated consistent anti-fibrotic effects in cell culture systems and animal models of NASH, liver injury, or metabolic disease

The peptides osteogenic effects combine with its anti-inflammatory properties to optimize bone repair in fractures, surgeries, and degenerative conditions

8,9,46,202 There are other data suggesting that NAMPT may be a useful biomarker for tumor progression