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Macroscopic observation revealed that erythema, scaling, and inflammation were moderately relieved in the CMH@lip@TCeO 2 and CMH@lip@Res groups compared to CMH@lip, with the most significant improvement observed in the CMH@lip@Res-TCeO 2 group

Increased levels of vitamin A and -tocopherol, another form of vitamin E, were associated with the hormones testosterone and estradiol

Inflammasome is a multi-protein complex assembled by natural immune recognition receptors in the cytoplasm, which can mediate the production of various inflammatory mediators such as IL-1 and is crucial for the occurrence of inflammatory reactions (Li et al., 2020c)