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Description
Abstract Microglia are resident macrophages of the central nervous system that have key functions in its development, homeostasis and response to damage and infection

While approximately 4500 of these genes are considered part of the druggable genome, currently, fewer than 700 of them have been targeted by drugs approved by the FDA

The fourth group, pre-cultured in hypoxia, was incubated with PBS for 30 min and DSNBD-GSH (10 M) for 30 min and imaged

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Methadone was generously supplied by the National Institute on Drug Abuse (NIDA, Rockville, MD)