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Sara Lonardi has received research funding from Merck Serono and Amgen Inc., honoraria for consulting/advisory roles from Amgen Inc., Bayer Healthcare, Merck Serono and Eli Lilly and Company, and honoraria for speakers bureau from Eli Lilly and Company, Bristol-Myers Squibb and Roche

Joosten, R

Treatment with FOXO4-DRI at 25 M in serum-limited senescent fibroblast and keloid organ culture models promoted apoptosis, decreased G0/G1 phase cells, and induced p53-pS15 nuclear exclusion confirmed by Annexin V-FITC/PI apoptosis assays and TUNEL staining of keloid organ cultures at days 3, 7, and 10

Results: HepG2-CYP2D6 * 1 and HepG2-CYP2D6 * 10 cell lines were successfully constructed

Our body naturally produces it, playing a crucial role in different physiological processes