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The increased risk is associated with: smoking diabetes (high blood sugar) excessive sun, tanning, and sunlamp exposure steroid medication if used long-term frequent head x-rays family history an eye disease like uveitis (long-term), retinitis pigmentosa, glaucoma, or retinal detachment

Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid

This is a mechanism no approved drug currently uses Phase 2 trials showed up to 24% body weight reduction over 48 weeks, meaningfully exceeding tirzepatide and semaglutide outcomes Phase 3 trials are currently underway

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Set reminders or schedule injections around training or meals (for oral versions)