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Diabetes mellitus, mitochondrial dysfunction, and Ca2+-dependent permeability transition pore

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This pathway is critical to maintain the key molecule antioxidant glutathione (GSH) in a reduced state, regulating oxidative stress levels (Fig
Metabolomics Cells were cultivated and metabolites extracted for metabolite quantification by HPLC but followed by filtration through a VIVASPIN 500 3KDa cut-off filters (Sartorius AG) then kept at 80 C until shipped on dry ice to Human Metabolome Technologies (HMT) for analysis

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