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doi: 10.3389/fnagi.2015.00052 150

Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies

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Thus, Pic plays an important role in MUC2 barrier disruption in the intestine (44), promoting mucus layer penetration and attachment to the epithelium, and hence, is a virulence factor
NAPQI can be detoxified by subsequent phase II metabolism via conjugation with glutathione (GSH), partly mediated by different glutathione S -transferase (GST) isozymes (Figure 1) (Mitchell et al., 1973b)
