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We can imagine that similar interruptions and chaotic responses are going on in other areas of the brain and the central nervous system, potentially causing significant unusual, unpredictable reactions and cross-reactions

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Long-term AAS use has been linked to glomerular hypertrophy and focal segmental glomerulosclerosis, likely secondary to hyperfiltration, systemic hypertension, and dyslipidaemia

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Oxidative stress also affects the renin-angiotensin-aldosterone system (RAAS), a hormonal system that regulates blood pressure and fluid balance [79]