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Description
Patients randomized to metformin therapy in the Diabetes Prevention Program Outcome Study were more likely to show vitamin B12 deficiency or borderline low vitamin B12 levels (19)
For reference, one standard drink contains 14 g of alcohol, so having a couple drinks a day can have a cumulative impact on vitamin B12
Routine B12 testing is not recommended for asymptomatic individuals without risk factors
Macrocytic anemia (elevated MCV, above 100 fL) most commonly indicates B12 or folate deficiency
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