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All assays were thus performed (or quality controlled) and interpreted according to the manufacturers instructions in accredited laboratories adhering to Good Clinical Laboratory Practices (GCLP)

Metabolic Regulation: Activation of hypothalamic MC4R suppresses appetite (anorexigenic) and increases energy expenditure via sympathetic nervous system stimulation of brown fat thermogenesis

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SafdarABourgeoisJMOgbornDILittleJPHettingaBPAkhtarMet alEndurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

C.et al (2003)