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Using a luciferase reporter assay, the authors confirmed that miR-181a, miR-135a and miR-302c targeted directly PLAG1 which is an IGF2 transcription factor (102)
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412 Notably, GLP-1RAs, including exendin-4, have been shown to attenuate microglial activation, resulting in a reduction in the expression of proinflammatory cytokines such as TNF- and IL-1
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Weekly Journal Scan: REDEFINing the next generation of obesity pharmacotherapy
