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Kizhakkayil J, Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S

Thats the science behind Immunocal by Immunotec, trusted for over 25 years to help your cells perform at their best
doi: 10.1016/j.jcis.2017.09.072

It is known that some polymorphism of MTHFR would result in reduction of MTHFR enzyme activity as well as DNA methylation process, later shown to have significant impacts in various psychiatric diseases

Tolerance development : Effects diminish over time, requiring higher doses
