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Beyond presynaptic deficits, chronic dopamine depletion leads to postsynaptic adaptations, including downregulation of D2/3 receptors and inflammationmediated desensitization of downstream signaling pathways [201]

Role of glutamate transporters in the regulation of glutathione levels in human macrophages

Apart from the well-documented GPx-like catalytic activity, ebselen is also reported for directly scavenging the biologically relevant ROS (like peroxyl and singlet oxygen) and reactive nitrogen species (peroxynitrite) with rate constants comparable to standard antioxidants

Characteristics of the aging skin

HDACs are a class of enzymes that regulate gene expression by removing acetyls from histones and play an important role in cell regulation and disease development [60]