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[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Larsen S.M., Levine L.A
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The presence of the SH3 domain allows p85 and p110 to form a heterodimer and the presence of the SH2 domains allows the heterodimer to bind to phosphorylated tyrosine docking sites on growth factor receptors harboring intrinsic tyrosine kinase activity such as the epidermal growth factor receptor (EGFR)
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