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Anti-tumor necrosis factor therapy in patients with difficult to treat Takayasu arteritis

Aug 2022;53(8):2702-2708

With regard to distribution , for drugs such as diazepam 1 and penfluridol 5 that are substantially distributed into adipose tissue, greater adiposity is associated with greater storage of the drug in lipid reservoirs, and hence greater availability of the drug for return to blood as blood levels fall due to metabolism

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Peer review Peer review information Nature Medicine thanks John Wilding and the other, anonymous, reviewer(s) for their contribution to the peer review of this work