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Kraft MD, Btaiche IF, Sacks GS, et al

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In an ADNP-deficient mouse model (ADNP +/ ), which presents with increased tau hyperphosphorylation, tauopathy-induced memory impairments, and neurodegeneration, 2 weeks of daily 0.5 g IN-NAP to 2 and 9 month old mice partially ameliorated cognitive deficits and reduced tau hyperphosphorylation, showing that even short-term treatment can have significant effects on MCI/AD phenotypes at various stages of degeneration [105]

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A cervical epidural steroid injection (CESI) is an injection of anti-inflammatory medicine (a steroid) into the epidural space in your neck