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Intriguingly, CEBPB also participates in HPV oncogene regulation: while it represses the HPV-18 long control region (LCR) via CEBPB, IL6/STAT3 signaling dominantly activates the LCR, highlighting a context-dependent interplay between CEBPB and viral oncogenesis [120]
CEBPB also interacts with ATF5 and CEBPD, forming heterodimers that sustain tumor cell survival, while dominant-negative peptides targeting these interactions induce apoptosis [154, 155]
Liang, X
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A., Marcotrigiano, J
