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The precise aetiology of this neuronal death is indeterminate
L.MayfieldR
C.SimpsonK
In a tramadol-induced hepatotoxicity rat model, supplemental lycopene at 15 mg/kg body weight for 15 days mitigated the hepatotoxicity by increasing antioxidant activity, reducing fatty acid breakdown and necrosis, lipid peroxidation, inhibiting DNA fragmentation, and apoptosis [115]
S.SchlegelJ.CotgreaveI
