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Simultaneously, another PD-related study has revealed that Sirtuin 1 (SIRT1), a NAD + -dependent protein deacetylase, plays a critical role in maintaining lactate homeostasis in the brain by inhibiting PKM2 through deacetylation 8

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[0107] Embodiment 100: The antibody according to any one of embodiments 1-8, wherein said antibody comprises a heavy chain variable region (VH) of an M25AELFDS antibody and a light chain variable region (VL) of an M25AELFDS antibody
