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Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin

HDL in the 21st century: a multifunctional roadmap for future HDL research

doi: 10.1111/j.1360-0443.2006.01782.x
Low levels may be a sign of adrenal gland disorders (such as Cushing's syndrome and aldosteronism), kidney disease, or alcohol use disorder