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Interestingly, they found that the donor HSCs engrafted and successfully replaced the defective erythroid lineage

For example, both IGFBP-2 and IGFBP-5 bind IGF-1 at a higher affinity than it binds its receptor

10.1128/JB.00647-09 J

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doi: 10.1158/1535-7163.MCT-13-0208 227 PraharajMShenFLeeAJZhaoLNirschlTRTheodrosDet al
