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Most of the data, I will say, are from looking at people who first received the AstraZeneca vaccinewhich is made from the same technology that created the J&J vaccinethat really does show important boosting of the protective effect with an mRNA vaccine given as a second dose

Almost all of it comes from studies of the two peptides individually , in animals , not from trials of the combination in people

Wegovy EPAR product information European Medicines Agency

And the gastrointestinal side effects of semaglutide, particularly nausea and acid reflux, can make restful sleep difficult
