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The two peripheral membrane proteins, synexin and sorcin are predominantly associated with the second type of lipid raft in RBC and become the major proteins in the Ca 2+ -induced nanovesicles (60 nm diameter) (Salzer et al., 2002)

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Mitochondria serve as central regulators in this process through several key mechanisms: 2.2.1 Metabolic substrate provision Mitochondria provide not only ATP but also intermediate metabolites from the TCA cycle (e.g., citrate, succinate, -ketoglutarate) that serve as precursors for the biosynthesis of lipids, proteins, and nucleic acids, which are crucial for rapid immune cell proliferation and cytokine production (8, 9)

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doi: 10.1159/000541881 177 DaiJLuYRocaHKellerJMZhangJMcCauleyLKet al

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